MEM-COG Project
The Mozart Effect on memory in patients with cognitive decline
The limited efficacy of drug therapy for treating dementia has pushed the interest of research toward finding non-pharmacological therapies as a complementary approach to treating cognitive decline. Among other therapies, music therapy has received great attention and several studies have investigated its potential benefits for behavioral deficits in Alzheimer’s disease (AD). Despite evidence that music therapy may be useful for behavioral symptoms related to dementia, there is scarce evidence concerning its positive effects on cognition and during the pre-clinal stages of AD such as mild cognitive impairment (MCI). However, recent evidence in healthy older adults indicates that exposure to music (as background) may improve performance while people are learning new information and/or retrieving stored information. Surprisingly, there is no available evidence that background music may also work for people with memory deficits, such as AD or MCI. The main aim of this project is to investigate whether background music acts as a memory enhancer in people with mild AD and MCI, based on previous evidence in healthy older adults. Indeed, long-term episodic memory is arguably the most affected cognitive ability in AD from disease onset at its pre-clinical stages, therefore, research should focus on these compensatory strategies to restore memory deficits.
Given that the aim of the project is to prove the efficacy of background music in enhancing memory, it is important to understand how this effect works. Some authors have suggested that using music as a background is a way of affording efficient strategies to bind new information to learning contexts. Indeed, it has been shown that providing participants with associative strategies reduces age-related associative deficits, indicating that older adults have difficulty binding memories. However, others claim that background music helps increase arousal and this, in turn, reinforces memory traces when encoding (Arousal-Mood hypothesis). In the context of this project, we aim to investigate alternative theories that explained the critical role of both background processes driven by context-dependent factors and the arousal induced by music.
PID2020-118672RB-I00
Research team

Principal Investigator, UOC

Hospital de la Santa Creu i Sant Pau

Ph.D. Student, UOC
Scientific articles
Calabria, M., Ciongoli, F., Grunden, N., Ordás, C., & García-Sánchez, C. (2023). Background music and memory in Mild Cognitive Impairment: the role of interindividual differences. Journal of Alzheimer’s Disease, 1-15. Full text (OA) here
Outreach activity
- Arteterapia: ¿tiene beneficios en el deterioro cognitivo? Blog Salud con Ciencia 2023
- La música pot millorar l’aprenentatge? Nit de la Recerca 2022
- El baile de nuestros genes al ritmo de la música SINC, enero 2023
- The Conversation ¿Por qué muchas personas con alzhéimer recuerdan bien canciones de su juventud?
Radio interviews
- Inquietamente – RTVE Música como regulador emocional y activador de memoria
- Artesfera – Radio Exterior de España El consumo musical puede influir en nuestra memoria
- Radio Autonomica Galega – A tarde (min. 35:45)
- Radio Cope La música podria ajudar a la memòria de persones amb Alzheimer
- Cadena SER ‘A vivir que son dos días’ ¿Te sabes las letras de las canciones?
Press releases and newspapers
- Journal of Alzheimer’s Disease The beneficial effects of music on memory may depend on how it is listened to
- Corriere della Sera «Effetto Mozart», così la musica può migliorare memoria e apprendimento e combattere il declino cognitivo
- La Vanguardia Escuchar música “activadora” mejora el rendimiento cognitivo, según la UOC
- Univadis de Medscape Los hábitos de consumo musical pueden influir en los beneficios de la música sobre la memoria
- UOC La música de fondo podría mejorar la memoria de personas con Alzheimer o deterioro cognitivo
- SINC La música de fondo podría mejorar la memoria en el Alzhéimer o deterioro cognitivo
- La Vanguardia Estudian si la música de fondo mejora la memoria de personas con Alzheimer
- ElDiario.es Estudian si la música de fondo mejora la memoria de personas con Alzheimer